EMD-71278

Single-particle
2.2 Å
EMD-71278
3D View Gallery
Deposition: 17/06/2025
Map released: 15/04/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71278
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9p4q summary report (pdf.gz) Map and 9p4q FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of AAV.CAP-B10 complexed to AAVR-PKD2

EMD-71278

Single-particle
2.2 Å
EMD-71278
3D View Gallery
Deposition: 17/06/2025
Map released: 15/04/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: CAP-B10, Adeno-associated virus, Mus musculus
Sample: CAP-B10
Fitted models: 9p4q

Deposition Authors: Brittain TJ , Jang S
Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids.
Brittain TJ , Jang S , Coughlin GM, Hoang JD, Barcelona BH, Giriat I, Ristic F, Appling N, Chossis CPMA, Shay TF, Gradinaru V
(2026) Mol Ther
PUBMED: 41906393
DOI: doi:10.1016/j.ymthe.2026.03.030
ISSN: 1525-0024