EMD-70919

Single-particle
3.2 Å
EMD-70919
3D View Gallery
Deposition: 31/05/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70919
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ovu summary report (pdf.gz) Map and 9ovu FULL report (pdf.gz)
EMICSS annotations (xml)

Composite map of GluA1/A2 in the activated state, in complex with positive allosteric modulator (R,R)-2b and agonist glutamate (ATD-LBD-TMD)

EMD-70919

Single-particle
3.2 Å
EMD-70919
3D View Gallery
Deposition: 31/05/2025
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Heteromeric GluA1A2 with positive allosteric modulator (R,R)-2b and agonist glutamate (Glu)
Fitted models: 9ovu

Deposition Authors: Yen LY, Sobolevsky AI, Newton TP, Gangwar SP
Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core.
Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI
(2026) Nat Commun
PUBMED: 41904128
DOI: doi:10.1038/s41467-026-71063-1
ISSN: 2041-1723