EMD-70722

Single-particle
3.2 Å
EMD-70722
3D View Gallery
Deposition: 19/05/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70722
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9opr summary report (pdf.gz) Map and 9opr FULL report (pdf.gz)
EMICSS annotations (xml)

TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody

EMD-70722

Single-particle
3.2 Å
EMD-70722
3D View Gallery
Deposition: 19/05/2025
Map released: 13/05/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Fitted models: 9opr

Deposition Authors: McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M, Case JB, Brown JT, Park YJ, Lee J, Sutherland E, Aggarwal A, Gibson C, Lempp FA, Stewart C, Tortorici MA, Sanapala S, Low JS, Asarnow D, Bohan D, Dellota Jr E, Merz B, Chawla B, Kar S, Lanzavecchia A, Sallusto F, Riley NM, Turville S, Purcell L, Diamond MS, Veesler D
(2026) Nat Struct Mol Biol
PUBMED: 42050172
DOI: doi:10.1038/s41594-026-01801-y
ISSN: 1545-9985
Grant Support: