EMD-70601

Single-particle
3.3 Å
EMD-70601
3D View Gallery
Deposition: 13/05/2025
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70601

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9olx summary report (pdf.gz) Map-9olx FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of a constitutively open human TRPC3 mutant in the inhibited state

EMD-70601

Single-particle
3.3 Å
EMD-70601
3D View Gallery
Deposition: 13/05/2025
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human TRPC3 T573A/Delta 28 mutant/GSK417651A tetrameric complex
Fitted models: 9olx

Deposition Authors: Bell B , Baker ML , Cordero-Morales JF
Functional and structural basis of a hypermorphic TRPC3 variant.
Bell B , Jaramillo-Granada AM , Romero LO , Gutierrez IA, Mallampalli VKPS, Fan G , Varma S , Baker ML , Serysheva II , Vasquez V , Cordero-Morales JF
(2026) Sci Adv , 12 , eaec9284 - eaec9284
PUBMED: 41880503
DOI: doi:10.1126/sciadv.aec9284
ISSN: 2375-2548