EMD-70338
Cryo-EM structure of modified Zika virus E protein dimer complexed with a neutralizing antibody SMZAb2 Fab
EMD-70338
Single-particle4.09 Å
Deposition: 25/04/2025Map released: 21/01/2026
Last modified: 21/01/2026
Sample Organism:
Zika virus,
Homo sapiens
Sample: Zika virus E protein dimer complex with a neutralizing antibody SMZAB2 Fab
Fitted models: 9od2
Deposition Authors: Galkin A, Pozharski E
Sample: Zika virus E protein dimer complex with a neutralizing antibody SMZAB2 Fab
Fitted models: 9od2
Deposition Authors: Galkin A, Pozharski E
Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk.
Wang Y ,
Galkin A,
Shang X,
Marin A,
Jin S,
Ye TJ ,
Bale S,
Chiang CI ,
Chowdhury A,
Chenine AL,
Turonis A,
Greenhouse J,
Stone R,
Wear J,
Kar S,
Andersen H ,
Huang YS ,
Vanlandingham DL,
Higgs S,
Lapidus RG,
Fuerst T,
Weber DJ ,
Wyatt RT,
Iffland C,
Pierson TC,
Andrianov AK ,
Pozharski E ,
Li Y
(2025) Nat Commun , 16 , 11558 - 11558
,
Galkin A,
Shang X,
Marin A,
Jin S,
Ye TJ ,
Bale S,
Chiang CI ,
Chowdhury A,
Chenine AL,
Turonis A,
Greenhouse J,
Stone R,
Wear J,
Kar S,
Andersen H ,
Huang YS ,
Vanlandingham DL,
Higgs S,
Lapidus RG,
Fuerst T,
Weber DJ ,
Wyatt RT,
Iffland C,
Pierson TC,
Andrianov AK ,
Pozharski E ,
Li Y
(2025) Nat Commun , 16 , 11558 - 11558
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