EMD-67624

Single-particle
3.34 Å
EMD-67624
3D View Gallery
Deposition: 11/12/2025
Map released: 01/04/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67624

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-21fg summary report (pdf.gz) Map-21fg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human P2X3 receptor in the ATP- and sivopixant-bound closed state

EMD-67624

Single-particle
3.34 Å
EMD-67624
3D View Gallery
Deposition: 11/12/2025
Map released: 01/04/2026
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human P2X3 trimer
Fitted models: 21fg

Deposition Authors: Hattori M , Zhao Z
Structure of the human P2X3 receptor reveals the basis for subtype-selective inhibition by sivopixant.
Zhao Z, Wang DP, Zhang X, Gao Y, Xu H, Teng X, Shen C, Chen J, Zhang J, Guo CR, Hattori M
(2026) PLoS Biol , 24 , e3003777 - e3003777
PUBMED: 42018567
DOI: doi:10.1371/journal.pbio.3003777
ISSN: 1545-7885