EMD-67575

Single-particle
3.29 Å
EMD-67575
3D View Gallery
Deposition: 08/12/2025
Map released: 11/03/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67575

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-21cq summary report (pdf.gz) Map-21cq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of DICER-D991G-H992G/26S-GU complex in dicing state

EMD-67575

Single-particle
3.29 Å
EMD-67575
3D View Gallery
Deposition: 08/12/2025
Map released: 11/03/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of DICER-D991G-H992G/26S-GU in dicing state
Fitted models: 21cq

Deposition Authors: Ngo MK
DICER cleavage fidelity is governed by 5'-end binding pockets.
Ngo MK, Le CT , Nguyen TA
(2026) Nature , 653 , 611 - 620
PUBMED: 41781616
DOI: doi:10.1038/s41586-026-10211-5
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: