EMD-66871

Single-particle
2.39 Å
EMD-66871
3D View Gallery
Deposition: 31/10/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66871

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9xha summary report (pdf.gz) Map-9xha FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of unnatural-base aptamer AptD2 with DENV2 NS1

EMD-66871

Single-particle
2.39 Å
EMD-66871
3D View Gallery
Deposition: 31/10/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Dengue virus 2 Thailand/16681/84, synthetic construct
Sample: Cryo-EM structure of unnatural-base aptamer AptD2 with DENV2 NS1
Fitted models: 9xha

Deposition Authors: Sawada K , Sano FK , Shuto Y , Hirano H , Kusakizako T , Itoh Y , Kise Y , Nureki O

Structural Insights into Enhanced Binding Affinity and Specificity of Six-Letter DNA Aptamers to Dengue Antigen NS1 Proteins via Genetic Alphabet Expansion
Sawada K , Kimoto M , Matsunaga K , Tan HP , Takayanagi R , Sano FK , Shuto Y , Hirano H , Kusakizako T , Itoh Y , Kise Y , Hirao I , Nureki O
To Be Published