EMD-66136

Single-particle
3.25 Å
EMD-66136
3D View Gallery
Deposition: 08/09/2025
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-66136

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9wp9 summary report (pdf.gz) Map-9wp9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the d18:1 S1P-bound S1PR3 and Gq complex

EMD-66136

Single-particle
3.25 Å
EMD-66136
3D View Gallery
Deposition: 08/09/2025
Map released: 26/11/2025
Last modified: 26/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: d18:1 S1P-bound S1PR3 in complex with Gq
Fitted models: 9wp9

Deposition Authors: Im D , Asada H, Iwata S, Yamauchi M , Hagiwara M
Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3-G q complexes.
Yamauchi M , Im D , Maeda S , Ikuta T , Toyomoto M , Asada H, Sugita Y , Kishikawa JI , Noda T , Kato T , Inoue A , Iwata S, Hagiwara M
(2025) PNAS , 122 , e2507421122 - e2507421122
PUBMED: 41252158
DOI: doi:10.1073/pnas.2507421122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: