EMD-65887

Single-particle
2.35 Å
EMD-65887
3D View Gallery
Deposition: 18/08/2025
Map released: 01/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65887

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9wda summary report (pdf.gz) Map-9wda FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 microtubule

EMD-65887

Single-particle
2.35 Å
EMD-65887
3D View Gallery
Deposition: 18/08/2025
Map released: 01/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 microtubule
Fitted models: 9wda

Deposition Authors: Ti SC, Luo JY , Khoo CJ
An evolution-conserved allosteric network in human tubulin governs paclitaxel efficacy.
Luo J, Khoo CJ , Chen W, Liu Z, Li B, Lau WS, Li XD , Ti SC
(2026) Nat Chem Biol
PUBMED: 41986561
DOI: doi:10.1038/s41589-026-02204-2
ISSN: 1552-4469