EMD-65637

Single-particle
2.7 Å
EMD-65637
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65637

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w4l summary report (pdf.gz) Map-9w4l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of inhibitor M353-0039 bound urea transporter A2.

EMD-65637

Single-particle
2.7 Å
EMD-65637
3D View Gallery
Deposition: 31/07/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotrimer complex of human urea transporter
Fitted models: 9w4l

Deposition Authors: Huang S, Sun J
Hotspot pocket-based discovery of urea transporter selective inhibitors.
Liu L, Li Z, Zhang C, Zhang Y, Huang Z, Zhang D, Li D, Zhao J, Miao Y, Cai B, Zhu K, Sun JP, Hou G, Sun Y, Yang B, Yu X, Huang S
(2026) Nat Commun , 17
PUBMED: 42009654
DOI: doi:10.1038/s41467-026-71834-w
ISSN: 2041-1723