EMD-65622

Single-particle
2.9 Å
EMD-65622
3D View Gallery
Deposition: 31/07/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65622
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9w49 summary report (pdf.gz) Map and 9w49 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human kappa opioid receptor -G protein signaling complex bound with U-50488H

EMD-65622

Single-particle
2.9 Å
EMD-65622
3D View Gallery
Deposition: 31/07/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Kappa-type opioid receptor-Gi protein-bound U-50488
Fitted models: 9w49

Deposition Authors: Suno-Ikeda C, Takai T, Hirose M, Inoue A, Sugita Y, Kato T, Kobayashi T, Suno R
Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Suno-Ikeda C, Nishikawa R, Suzuki R, Yokoi S, Iwata S, Takai T, Ogura T, Hirose M, Tokuda A, Katamoto R, Inoue A, Asai E, Kise R, Sugita Y, Kato T, Nagase H, Mitsutake A, Saitoh T, Katayama K, Inoue A, Kandori H, Kobayashi T, Suno R
(2025) Nat Commun , 16 , 9392 - 9392
PUBMED: 41152269
DOI: doi:10.1038/s41467-025-64882-1
ISSN: 2041-1723