EMD-65599

Single-particle
3.04 Å
EMD-65599
3D View Gallery
Deposition: 29/07/2025
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65599

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w3f summary report (pdf.gz) Map-9w3f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human beta2-adrenergic receptor in complex with a novel antagonist

EMD-65599

Single-particle
3.04 Å
EMD-65599
3D View Gallery
Deposition: 29/07/2025
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Cryo-EM structure of the human beta2-adereneegic receptor in complex with a novel antagonist
Fitted models: 9w3f

Deposition Authors: Xu T, Liu X
A negative survival pressure selection system enables GPCR antagonist screening.
Xu T, Sun Q, Zhang S, Liu T, Sun X, Wang X, Lin B, Liu Z, Wang J, He G, Liu X
(2026) Cell Discov , 12
PUBMED: 42129146
DOI: doi:10.1038/s41421-026-00892-7
ISSN: 2056-5968