EMD-65573

Single-particle
2.82 Å
EMD-65573 Deposition: 28/07/2025
Map released: 17/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65573

Cryo-EM structure of Peptide 383 (P383)-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70

EMD-65573

Single-particle
2.82 Å
EMD-65573 Deposition: 28/07/2025
Map released: 17/06/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama, synthetic construct
Sample: Cryo-EM structure of Peptide 383 (P383)-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70
Fitted models: 9w2j

Deposition Authors: Ren Y, Pavlovskyil A, Liu X, Gerhart-Hines Z

Mechanistic basis for activation and selectivity of NK2R by endogenous and synthetic peptide agonists