EMD-65508

Single-particle
3.8 Å
EMD-65508
3D View Gallery
Deposition: 24/07/2025
Map released: 03/06/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65508

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9w0m summary report (pdf.gz) Map-9w0m FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of S1P2 in complex with heterotrimeric G protein

EMD-65508

Single-particle
3.8 Å
EMD-65508
3D View Gallery
Deposition: 24/07/2025
Map released: 03/06/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary complex of s1p2 with G protein heterotrimeric
Fitted models: 9w0m

Deposition Authors: Wu B, Zhao Q, Tan Q, Zhao Q, Wu B
Structural basis of allosteric and bitopic ligands binding in sphingosine-1-phosphate receptors 2 and 3.
Wu Y, Chen Q, Wang H, Liu K, Wei J, Wang M, Chen K, Zhu Y, Han S, Yi C, Ma L, Schnapp G, Pautsch A, Gnamm C, Grauert M, Schmidt E, Tan Q, Wu B, Zhao Q
(2026) Protein Cell , 17 , 662 - 668
PUBMED: 40851516
DOI: doi:10.1093/procel/pwaf068
ISSN: 1674-8018