EMD-65442

Single-particle
2.66 Å
EMD-65442
3D View Gallery
Deposition: 20/07/2025
Map released: 29/04/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65442

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vxv summary report (pdf.gz) Map-9vxv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of Nipah Virus Polymerase in complex with ERDRP-0519

EMD-65442

Single-particle
2.66 Å
EMD-65442
3D View Gallery
Deposition: 20/07/2025
Map released: 29/04/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Henipavirus nipahense
Sample: Cryo-EM Structure of Nipah Virus Polymerase in complex with ERDRP-0519
Fitted models: 9vxv

Deposition Authors: Xue L, Gui J, Chang T, Pan H, Xiong X
Differential inhibition of Morbillivirus and Henipavirus polymerases by ERDRP-0519 and structure-guided inhibitor optimization.
Xue L, Gui J, Gao S, Gao X, Chang T, Pan H, Tang J, Zhang M, Li Z, Zou B, Zhao H, Wang L, Li M, Rong L, Plemper RK, Chen X, He J, Pei R, Zhan P, Xiong X
(2026) Cell , 189 , 4094
PUBMED: 42061399
DOI: doi:10.1016/j.cell.2026.04.011
ISSN: 1097-4172