EMD-65097

Single-particle
3.06 Å
EMD-65097
3D View Gallery
Deposition: 19/06/2025
Map released: 10/09/2025
Last modified: 29/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65097

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9vix summary report (pdf.gz) Map-9vix FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

human alpha 7 nicotinic acetylcholine receptor L278A mutant in complex with L-nicotine (desensitized state)

EMD-65097

Single-particle
3.06 Å
EMD-65097
3D View Gallery
Deposition: 19/06/2025
Map released: 10/09/2025
Last modified: 29/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human alpha 7 nicotinic acetylcholine receptor L278A mutant in complex with L-nicotine
Fitted models: 9vix

Deposition Authors: Liu S , Chen H , Tian C
Structural insights into the progressive recovery of alpha 7 nicotinic acetylcholine receptor from nicotine-induced desensitization.
Liu S , Chen H , Zhu X , Ye F, Zhao Y, Qin J , Zheng Y, Wang X, Zhang L, Chen H , Li X , Mu W, Fu Y, Luo C , Hou H , Bai C , Liu L , Tian C
(2025) Sci Adv , 11 , eadx4432 - eadx4432
PUBMED: 41071887
DOI: doi:10.1126/sciadv.adx4432
ISSN: 2375-2548
Grant Support: