EMD-64640

Single-particle
3.24 Å
EMD-64640
3D View Gallery
Deposition: 16/05/2025
Map released: 06/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64640

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9uz7 summary report (pdf.gz) Map-9uz7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the nucleosome core particle with site-specific DNA-histone crosslinking

EMD-64640

Single-particle
3.24 Å
EMD-64640
3D View Gallery
Deposition: 16/05/2025
Map released: 06/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human canonical histone and 601 DNA
Fitted models: 9uz7

Deposition Authors: Zhou CZ, Li HT, Shan XJ, Ji GY
DNA-histone cross-link locks the nucleosome structure and disrupts its recognition and processing.
Shan X, Ji G, Li J, Ren M, Ma J, Zhou Y, Li H, Zhou C
(2026) Protein Cell , 17 , 476 - 482
PUBMED: 41206067
DOI: doi:10.1093/procel/pwaf094
ISSN: 1674-8018