EMD-63850

Single-particle
4.14 Å
EMD-63850 Deposition: 19/03/2025
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63850

Focused refinement of 19S in the substrate-engaged human 26S proteasome bound to midnolin with RPT6 at top of spiral staircase

EMD-63850

Single-particle
4.14 Å
EMD-63850 Deposition: 19/03/2025
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 26S proteasome complexed with midnolin
Fitted models: 9u4m

Deposition Authors: Zhu C , Qin L, Liang L
Structural dynamics of the midnolin-proteasome during ubiquitin-independent substrate turnover.
Zhu C , Qin L, Dai Z , Zuo P , Yang A, Zhong L, Lin Z , Liang L
(2026) Nat Commun , 17
PUBMED: 41896529
DOI: doi:10.1038/s41467-026-71002-0
ISSN: 2041-1723