EMD-63785

Helical reconstruction
3.55 Å
EMD-63785
3D View Gallery
Deposition: 17/03/2025
Map released: 04/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63785

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mc2 summary report (pdf.gz) Map-9mc2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of dopaminated Tau fibril

EMD-63785

Helical reconstruction
3.55 Å
EMD-63785
3D View Gallery
Deposition: 17/03/2025
Map released: 04/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of dopaminated Tau fibril
Fitted models: 9mc2

Deposition Authors: Liu Z, Li X , Liu C
Dopamine-Induced Tau Modification Prevents Pathological Phosphorylation and Generates a Distinct Fibril Polymorph.
Liu Z, Li X , Wang Q, Liu K, Zeng W, Li D, Zhao K, Ma Y, Long H, Zhang S , Li D, Sun B , Le W , Wang C , He Z, Kang W, Xiao W, Liu C
(2026) J Am Chem Soc , 148 , 4729 - 4742
PUBMED: 41555553
DOI: doi:10.1021/jacs.5c22156
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: