EMD-63228

Single-particle
2.94 Å
EMD-63228
3D View Gallery
Deposition: 20/01/2025
Map released: 21/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63228

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ln7 summary report (pdf.gz) Map-9ln7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Alpha-7 nicotinic acetylcholine receptor bound to inhibitory bicyclic peptide KP2007 in a resting state.

EMD-63228

Single-particle
2.94 Å
EMD-63228
3D View Gallery
Deposition: 20/01/2025
Map released: 21/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Alpha-7 nicotinic acetylcholine receptor bound to inhibitory bicyclic peptide KP2007 in a resting state.
Fitted models: 9ln7

Deposition Authors: Chen H, Sun D, Tian C
De novo discovery of unnatural and potent conotoxin-like bicyclic peptides through a phage-encoded library
Cao X, Chen H, Wang X, Yang X, Wang T, Zhou L, Shi C, Liu S, Tian C, Sun D
(2025) Sci China Chem , 68 , 4276 - 4284
DOI: doi:10.1007/s11426-024-2543-1
ISSN: 1862-2771