EMD-63204

Single-particle
2.61 Å
EMD-63204
3D View Gallery
Deposition: 17/01/2025
Map released: 04/03/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-63204
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9llj summary report (pdf.gz) Map and 9llj FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of D1R-Gs in complex with de novo designed GEM targetingTM1/2/4 and GEM targeting TM3/4/5, and agonist-positive allosteric GEM targeting TM5/6/7

EMD-63204

Single-particle
2.61 Å
EMD-63204
3D View Gallery
Deposition: 17/01/2025
Map released: 04/03/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Lama glama
Sample: Complex of D1R-Gs with de novo designed GEM targetingTM1/2/4 and GEM targeting TM3/4/5, and agonist-positive allosteric GEM targeting TM5/6/7
Fitted models: 9llj

Deposition Authors: Guo J, Zhou Y, Cheng S, Zhang Y

GPCR exoframe modulator
Cheng S, Guo J, Zhou Y, Zhang Y
To Be Published