EMD-62885

Single-particle
3.22 Å
EMD-62885
3D View Gallery
Deposition: 27/12/2024
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62885

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9l8l summary report (pdf.gz) Map-9l8l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of GPCR megacomplex bound to agonists

EMD-62885

Single-particle
3.22 Å
EMD-62885
3D View Gallery
Deposition: 27/12/2024
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Rattus norvegicus
Sample: Structure of beta1-AR-Gs complex bound to epinephrine and an allosteric modulator
Fitted models: 9l8l

Deposition Authors: He G , Sun Q , Liu X , Liu X
A GPCR-G protein-beta-arrestin megacomplex enabled by a versatile allosteric modulator.
He G , Sun Q , Xu X, Kong F, Zhang S, Ye K, Sun X, Lin B, Chen X, Yan C, Liu X
(2026) Cell , 189 , 1434 - 1450.e22
PUBMED: 41605208
DOI: doi:10.1016/j.cell.2025.12.023
ISSN: 1097-4172