EMD-62884

Single-particle
3.22 Å
EMD-62884 Deposition: 27/12/2024
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62884

Structure of beta1-AR-Gs complex bound to epinephrine and an allosteric modulator

EMD-62884

Single-particle
3.22 Å
EMD-62884 Deposition: 27/12/2024
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Rattus norvegicus, Lama glama
Sample: Structure of beta1-AR-Gs complex bound to epinephrine and an allosteric modulator
Fitted models: 9l84

Deposition Authors: Sun Q , He G , Xu X , Liu X
A GPCR-G protein-beta-arrestin megacomplex enabled by a versatile allosteric modulator.
He G , Sun Q , Xu X , Kong F, Zhang S, Ye K, Sun X, Lin B, Chen X, Yan C, Liu X
(2026) Cell , 189 , 1434 - 1450.e22
PUBMED: 41605208
DOI: doi:10.1016/j.cell.2025.12.023
ISSN: 1097-4172