EMD-62774

Single-particle
3.55 Å
EMD-62774
3D View Gallery
Deposition: 17/12/2024
Map released: 19/03/2025
Last modified: 24/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62774

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9l2f summary report (pdf.gz) Map-9l2f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of SARM1 bound to M1 and 1AD in the active state

EMD-62774

Single-particle
3.55 Å
EMD-62774
3D View Gallery
Deposition: 17/12/2024
Map released: 19/03/2025
Last modified: 24/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Sarm1
Fitted models: 9l2f

Deposition Authors: Huang Y, Zhang J , Zheng S , Wang X
Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic.
Huang Y, Zhang J , Zhang W, Chen J, Chen S, Wu Q, Zheng S , Wang X
(2025) PNAS , 122 , e2424906122 - e2424906122
PUBMED: 39964720
DOI: doi:10.1073/pnas.2424906122
ISSN: 1091-6490
ASTM: PNASA6