EMD-62753

Single-particle
3.0 Å
EMD-62753
3D View Gallery
Deposition: 15/12/2024
Map released: 01/01/2025
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62753

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9l1s summary report (pdf.gz) Map-9l1s FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex

EMD-62753

Single-particle
3.0 Å
EMD-62753
3D View Gallery
Deposition: 15/12/2024
Map released: 01/01/2025
Last modified: 17/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: HER2 (S310F) - pertuzumab (T30S/D31A) complex
Fitted models: 9l1s

Deposition Authors: Xu L , Guo J
Computational-aided rational mutation design of pertuzumab to overcome active HER2 mutation S310F through antibody-drug conjugates.
Bai X, Xu L , Wang Z, Zhuang X, Ning J, Sun Y, Wang H, Guo Y, Xu Y, Guo J , Chen S , Pan L
(2025) PNAS , 122 , e2413686122 - e2413686122
PUBMED: 39793038
DOI: doi:10.1073/pnas.2413686122
ISSN: 1091-6490
ASTM: PNASA6