EMD-62283

Single-particle
2.92 Å
EMD-62283
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Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62283
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kdo summary report (pdf.gz) Map and 9kdo FULL report (pdf.gz)
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The structure of 2 ACTD bound to RNA polymerase II elongation complex with 3 CTG repeats

EMD-62283

Single-particle
2.92 Å
EMD-62283
3D View Gallery
Deposition: 03/11/2024
Map released: 12/11/2025
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae S288C, synthetic construct, Saccharomyces cerevisiae, Streptomyces sp.
Sample: The structure of 2 ACTD bound to RNA polymerase II elongation complex with 3 CTG repeats
Fitted models: 9kdo

Deposition Authors: Xu J , Zhao W , Zhu L
Stepwise transcription stalling by the anti-cancer drug Actinomycin D and insights into short tandem repeat transcription inhibition.
Zhao W , Zhu L , Liu Y, Deng W, Yang X, Ye L, Lin Z, Ding K, Yang X, Li X, Xu J
(2026) Nat Commun , 17
PUBMED: 41833943
DOI: doi:10.1038/s41467-026-70612-y
ISSN: 2041-1723