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EMD-62274

Composite map
Single-particle
3.3 Å
EMD-62274
3D View Gallery
Deposition: 03/11/2024
Map released: 07/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62274
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kdf summary report (pdf.gz) Map and 9kdf FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of Calcineurin-fusion Human endothelin receptor type-B in complex with RES-701-3

EMD-62274

Composite map
Single-particle
3.3 Å
EMD-62274
3D View Gallery
Deposition: 03/11/2024
Map released: 07/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Streptomyces venezuelae
Sample: Calcineurin-fusion Human endothelin receptor type-B in complex with RES-701-3
Fitted models: 9kdf

Deposition Authors: Shihoya W , Akasaka H , Nureki O
Structure of a lasso peptide bound ET B receptor provides insights into the mechanism of GPCR inverse agonism.
Shihoya W , Akasaka H , Jordan PA, Lechner A, Okada BK, Costa Machado da Cruz G, Sano FK , Tanaka T , Kawahara R, Chaudhari R, Masamune H, Burk MJ , Nureki O
(2025) Nat Commun , 16 , 3446 - 3446
PUBMED: 40263271
DOI: doi:10.1038/s41467-025-57960-x
ISSN: 2041-1723