EMD-62139
Structural and functional basis of antinociceptive action of conotoxin AoIA at the noradrenaline transporter
EMD-62139
Single-particle2.77 Å
Deposition: 22/10/2024Map released: 06/05/2026
Last modified: 23/09/2026
Sample Organism:
Homo sapiens,
Conus marmoreus
Sample: Cryo-EM structure of human norepinephrine transporter NET in an outward-open state in complex with a conotoxin ArXA-B
Fitted models: 9k6x
Deposition Authors: Zhang H, Harald S, Oliver B, Xu EH
Sample: Cryo-EM structure of human norepinephrine transporter NET in an outward-open state in complex with a conotoxin ArXA-B
Fitted models: 9k6x
Deposition Authors: Zhang H, Harald S, Oliver B, Xu EH
Structural and functional basis of antinociceptive action of chi-conotoxin AoIA at the noradrenaline transporter.
Belleza OJV 
,
Zhang H,
Schmidhammer H,
Gonzalez TI ,
Ciotu CI,
Tomasevic N,
Ocampo CMM ,
Fernando JC,
Koehbach J,
Schwarz P,
Al Makhlouf M ,
Tajti G,
Hasinger S,
Kastner N,
Avsar O,
Retzl B,
Jantsch K,
Jiang Y ,
Hellinger R,
Fischer MJM ,
Rosengren KJ ,
Gruber CW ,
Villaraza AJL ,
Stockner T ,
Spetea M ,
Xu HE ,
Sitte HH
(2026) Nat Struct Mol Biol , 33 , 1311 - 1323
,
Zhang H,
Schmidhammer H,
Gonzalez TI ,
Ciotu CI,
Tomasevic N,
Ocampo CMM ,
Fernando JC,
Koehbach J,
Schwarz P,
Al Makhlouf M ,
Tajti G,
Hasinger S,
Kastner N,
Avsar O,
Retzl B,
Jantsch K,
Jiang Y ,
Hellinger R,
Fischer MJM ,
Rosengren KJ ,
Gruber CW ,
Villaraza AJL ,
Stockner T ,
Spetea M ,
Xu HE ,
Sitte HH
(2026) Nat Struct Mol Biol , 33 , 1311 - 1323
Grant Support: