EMD-62127

Single-particle
3.0 Å
EMD-62127
3D View Gallery
Deposition: 22/10/2024
Map released: 22/10/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62127
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9k6h summary report (pdf.gz) Map and 9k6h FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of human LINE-1 ORF2p with endogenous DNA and RNA/cDNA hybrid bound to dNTP and Mn2+

EMD-62127

Single-particle
3.0 Å
EMD-62127
3D View Gallery
Deposition: 22/10/2024
Map released: 22/10/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Trichoplusia ni, Homo sapiens
Sample: Human LINE-1 ORF2p with endogenous DNA and RNA/cDNA hybrid bound to dNTP and Mn2+
Fitted models: 9k6h

Deposition Authors: Jin W , Yu C , Xu RM
Mechanism of DNA targeting by human LINE-1.
Jin W , Yu C , Zhang Y , Cao C , Xia T, Song G, Cai Z , Xue Y , Zhu B , Xu RM
(2025) Science , 390 , eadu3433 - eadu3433
PUBMED: 41066570
DOI: doi:10.1126/science.adu3433
ISSN: 1095-9203
ASTM: SCIEAS