EMD-61842

Single-particle
2.15 Å
EMD-61842
3D View Gallery
Deposition: 09/10/2024
Map released: 19/03/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61842

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9jvp summary report (pdf.gz) Map-9jvp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3

EMD-61842

Single-particle
2.15 Å
EMD-61842
3D View Gallery
Deposition: 09/10/2024
Map released: 19/03/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis H37Rv, Mycobacterium tuberculosis, Bos grunniens
Sample: CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 3
Fitted models: 9jvp

Deposition Authors: Zhou B, Zhao H, Gao Y , Chen X , Zhang T , He J , Xiong X
Structural Insights into Bortezomib-Induced Activation of the Caseinolytic Chaperone-Protease System in Mycobacterium tuberculosis.
Zhou B, Gao Y , Zhao H, Liu B, Zhang H, Fang C , Yuan H, Wang J, Li Z, Zhao Y, Huang X, Wang X, Oliveira ASF , Spencer J , Mulholland AJ , Burston SG , Hu J, Su N, Chen X , He J , Zhang T , Xiong X
(2025) Nat Commun , 16 , 3466 - 3466
PUBMED: 40216758
DOI: doi:10.1038/s41467-025-58410-4
ISSN: 2041-1723