EMD-61766
Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
EMD-61766
Single-particle3.8 Å
Deposition: 30/09/2024Map released: 22/01/2025
Last modified: 26/02/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus,
Homo heidelbergensis
Sample: Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
Fitted models: 9js4
Deposition Authors: Li J, Li H
Sample: Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
Fitted models: 9js4
Deposition Authors: Li J, Li H
Rapid restoration of potent neutralization activity against the latest Omicron variant JN.1 via AI rational design and antibody engineering.
Liao Y 
,
Ma H,
Wang Z,
Wang S,
He Y,
Chang Y,
Zong H,
Tang H,
Wang L ,
Ke Y,
Cai H ,
Li P ,
Tang J,
Chen H,
Drelich A ,
Peng BH ,
Hsu J ,
Tat V ,
Tseng CK ,
Song J,
Yuan Y ,
Wu M,
Liu J,
Yue Y,
Zhang X,
Wang Z,
Yang L,
Li J,
Ni X,
Li H,
Xiang Y,
Bian Y,
Zhang B ,
Yin H,
Dimitrov DS ,
Gilly J,
Han L,
Jiang H ,
Xie Y,
Zhu J
(2025) PNAS , 122 , e2406659122 - e2406659122
,
Ma H,
Wang Z,
Wang S,
He Y,
Chang Y,
Zong H,
Tang H,
Wang L ,
Ke Y,
Cai H ,
Li P ,
Tang J,
Chen H,
Drelich A ,
Peng BH ,
Hsu J ,
Tat V ,
Tseng CK ,
Song J,
Yuan Y ,
Wu M,
Liu J,
Yue Y,
Zhang X,
Wang Z,
Yang L,
Li J,
Ni X,
Li H,
Xiang Y,
Bian Y,
Zhang B ,
Yin H,
Dimitrov DS ,
Gilly J,
Han L,
Jiang H ,
Xie Y,
Zhu J
(2025) PNAS , 122 , e2406659122 - e2406659122
Grant Support: