EMD-61744

Single-particle
2.65 Å
EMD-61744
3D View Gallery
Deposition: 28/09/2024
Map released: 22/10/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61744

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9jqz summary report (pdf.gz) Map-9jqz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structural Insights into Selective Antagonism Grapiprant and EP4 Prostaglandin Receptor

EMD-61744

Single-particle
2.65 Å
EMD-61744
3D View Gallery
Deposition: 28/09/2024
Map released: 22/10/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: human prostaglandin E receptor EP4
Fitted models: 9jqz

Deposition Authors: Wu YL, Zhang H , Xu JY, Wu CR, Xu EH
Structural insights into selective and dual antagonism of EP2 and EP4 prostaglandin receptors.
Wu Y , Zhang H , Xu J , Wu K, Hu W, He X, Wang G, Wu C , Xu HE
(2025) EMBO J , 44 , 7242 - 7262
PUBMED: 41162752
DOI: doi:10.1038/s44318-025-00611-0
ISSN: 1460-2075
ASTM: EMJODG