EMD-61472

Single-particle
2.76 Å
EMD-61472
3D View Gallery
Deposition: 09/09/2024
Map released: 23/04/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61472

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9jh5 summary report (pdf.gz) Map-9jh5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Activation mechanism of CYSLTR2 by C16:0 ceramide

EMD-61472

Single-particle
2.76 Å
EMD-61472
3D View Gallery
Deposition: 09/09/2024
Map released: 23/04/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, Lama glama
Sample: C16:0-ceramide-CYSLTR2-Gq
Fitted models: 9jh5

Deposition Authors: Wang JL, Ding JH, Sun JP , Yu X
Sensing ceramides by CYSLTR2 and P2RY6 to aggravate atherosclerosis.
Zhang S , Lin H, Wang J, Rui J, Wang T, Cai Z, Huang S, Gao Y, Ma T, Fan R , Dai R, Li Z, Jia Y, Chen Q, He H , Tan J, Zhu S, Gu R, Dong Z , Li M, Xie E, Fu Y, Zheng J , Jiang C , Sun J, Kong W
(2025) Nature , 641 , 476 - 485
PUBMED: 40049228
DOI: doi:10.1038/s41586-025-08792-8
ISSN: 1476-4687
ASTM: NATUAS