EMD-61421

Single-particle
3.05 Å
EMD-61421
3D View Gallery
Deposition: 03/09/2024
Map released: 24/09/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61421

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9jeq summary report (pdf.gz) Map-9jeq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Histamine-bound Histamine receptor 3 H3R G protein complex

EMD-61421

Single-particle
3.05 Å
EMD-61421
3D View Gallery
Deposition: 03/09/2024
Map released: 24/09/2025
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Mus musculus
Sample: Cryo-EM structure of Histamine-bound Histamine receptor 3 H3R G protein complex
Fitted models: 9jeq

Deposition Authors: Jin SS, Zhang H, Jiang Y
Decoding ligand recognition and constitutive activation of histamine H3 and H4 receptors.
Jin SS, Zhang H, Yan JH, Wu CR, Cai XQ, Wu K, Wang MW, Xu HE, Yang DH, Jiang Y
(2026) Acta Pharmacol.Sin. , 47 , 186 - 196
PUBMED: 40877594
DOI: doi:10.1038/s41401-025-01633-4
ISSN: 1745-7254