EMD-61077
Cryo-EM structure of the g1:Ox-bound human GLP-1R-Gs complex
EMD-61077
Single-particle2.99 Å
Deposition: 05/08/2024Map released: 26/02/2025
Last modified: 23/07/2025
Sample Organism:
Homo sapiens,
Rattus norvegicus,
Bos taurus,
Lama glama,
synthetic construct
Sample: Cryo-EM structure of the g1 Ox-bound human GLP-1R-Gs complex
Fitted models: 9j1p
Deposition Authors: Fan S, Li J, Zhuang J, Zhou Q
,
Mai Y,
Lin B,
Wang M-W,
Wu C
Sample: Cryo-EM structure of the g1 Ox-bound human GLP-1R-Gs complex
Fitted models: 9j1p
Deposition Authors: Fan S, Li J, Zhuang J, Zhou Q
,
Mai Y,
Lin B,
Wang M-W,
Wu C
Disulfide-Directed Multicyclic Peptides with N-Terminally Extendable alpha-Helices for Recognition and Activation of G Protein-Coupled Receptors.
Fan S,
Li J,
Zhuang J,
Zhou Q ,
Mai Y,
Lin B,
Wang MW ,
Wu C
(2025) J Am Chem Soc , 147 , 4821 - 4832
,
Mai Y,
Lin B,
Wang MW ,
Wu C
(2025) J Am Chem Soc , 147 , 4821 - 4832
Grant Support:
- National Natural Science Foundation of China (NSFC): 91853112 (China)
- National Natural Science Foundation of China (NSFC): 22174119 (China)
- National Natural Science Foundation of China (NSFC): 82273961 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 21521004 (China)
- Other government: 20720210001
- Other government: 20720220005IQ
- Other government: IRT_17R66
- Other government: 2021ZD0203400
- Other government: ZDKJ2021028