EMD-61077

Single-particle
2.99 Å
EMD-61077
3D View Gallery
Deposition: 05/08/2024
Map released: 26/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-61077
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9j1p summary report (pdf.gz) Map and 9j1p FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the g1:Ox-bound human GLP-1R-Gs complex

EMD-61077

Single-particle
2.99 Å
EMD-61077
3D View Gallery
Deposition: 05/08/2024
Map released: 26/02/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, Lama glama, synthetic construct
Sample: Cryo-EM structure of the g1 Ox-bound human GLP-1R-Gs complex
Fitted models: 9j1p

Deposition Authors: Fan S, Li J, Zhuang J, Zhou Q , Mai Y, Lin B, Wang M-W, Wu C
Disulfide-Directed Multicyclic Peptides with N-Terminally Extendable alpha-Helices for Recognition and Activation of G Protein-Coupled Receptors.
Fan S, Li J, Zhuang J, Zhou Q , Mai Y, Lin B, Wang MW , Wu C
(2025) J Am Chem Soc , 147 , 4821 - 4832
PUBMED: 39688263
DOI: doi:10.1021/jacs.4c12808
ISSN: 1520-5126
ASTM: JACSAT