EMD-60798

Single-particle
3.16 Å
EMD-60798
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Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60798
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9iqy summary report (pdf.gz) Map and 9iqy FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human TRPV4 intracellular domain in complex with GTPase RhoA

EMD-60798

Single-particle
3.16 Å
EMD-60798
3D View Gallery
Deposition: 13/07/2024
Map released: 28/05/2025
Last modified: 03/09/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of human TRPV4 intracellular domain in complex with GTPase RhoA
Fitted models: 9iqy

Deposition Authors: Yuan Z , Ruan SS, Li SL
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis.
Wang J , Yuan Z , Yu N, Jiao Q, Zhou H, Liao W, Shan J, Ruan S, Zhao Y , Mo Y, Qi L, Li T, Fu J, Ke B , Xu Y , Qian X , Zhang J , Zhao Z, Li S, Wang R, Li H
(2025) Circulation , 152 , 519 - 536
PUBMED: 40518994
DOI: doi:10.1161/CIRCULATIONAHA.124.071884
ISSN: 1524-4539