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EMD-60797
Cryo-EM structure of the human TRPV4-RhoA in complex with AH001
EMD-60797
Single-particle3.37 Å
Deposition: 13/07/2024Map released: 28/05/2025
Last modified: 03/09/2025
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of the human TRPV4-RhoA in complex with AH001
Fitted models: 9iqx
Deposition Authors: Yuan Z
,
Ruan SS,
Li SL
Sample: Cryo-EM structure of the human TRPV4-RhoA in complex with AH001
Fitted models: 9iqx
Deposition Authors: Yuan Z
,
Ruan SS,
Li SL
Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis.
Wang J ,
Yuan Z ,
Yu N,
Jiao Q,
Zhou H,
Liao W,
Shan J,
Ruan S,
Zhao Y ,
Mo Y,
Qi L,
Li T,
Fu J,
Ke B ,
Xu Y ,
Qian X ,
Zhang J ,
Zhao Z,
Li S,
Wang R,
Li H
(2025) Circulation , 152 , 519 - 536
,
Yuan Z ,
Yu N,
Jiao Q,
Zhou H,
Liao W,
Shan J,
Ruan S,
Zhao Y ,
Mo Y,
Qi L,
Li T,
Fu J,
Ke B ,
Xu Y ,
Qian X ,
Zhang J ,
Zhao Z,
Li S,
Wang R,
Li H
(2025) Circulation , 152 , 519 - 536
Grant Support: