EMD-60578

Single-particle
2.65 Å
EMD-60578
3D View Gallery
Deposition: 18/06/2024
Map released: 09/04/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60578

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8zyt summary report (pdf.gz) Map-8zyt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of neurotensin receptor 1 in complex with beta-arrestin1 and SBI-553 (complex 3)

EMD-60578

Single-particle
2.65 Å
EMD-60578
3D View Gallery
Deposition: 18/06/2024
Map released: 09/04/2025
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NTSR1-beta-arrestin1 complex
Fitted models: 8zyt

Deposition Authors: Sun D, Li X, Yuan Q, Yin W , Xu HE , Tian C
Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator.
Sun D, Li X, Yuan Q, Wang Y, Shi P, Zhang H, Wang T, Sun W, Ling S , Liu Y, Lai J, Xie W, Yin W , Liu L , Xu HE , Tian C
(2025) Cell Res , 35 , 284 - 295
PUBMED: 40118988
DOI: doi:10.1038/s41422-025-01095-7
ISSN: 1001-0602