EMD-60349

Single-particle
3.2 Å
EMD-60349
3D View Gallery
Deposition: 30/05/2024
Map released: 26/02/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60349

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8zpm summary report (pdf.gz) Map-8zpm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM strucutre of CXCR4 complexed with antagonist AMD070

EMD-60349

Single-particle
3.2 Å
EMD-60349
3D View Gallery
Deposition: 30/05/2024
Map released: 26/02/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: AMD070-CXCR4-KOR-Nb6
Fitted models: 8zpm

Deposition Authors: Jiao HZ, Hu HL
Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
Sang X , Jiao H, Meng Q, Fang X, Pan Q, Zhou J, Qian T, Zhang W, Xu Y , An J, Huang Z, Hu H
(2025) PNAS , 122 , e2425795122 - e2425795122
PUBMED: 40063796
DOI: doi:10.1073/pnas.2425795122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: