EMD-60109
SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated)
EMD-60109
Single-particle4.12 Å
Deposition: 11/05/2024Map released: 21/08/2024
Last modified: 23/07/2025
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2,
synthetic construct
Sample: SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated)
Fitted models: 8zhn
Deposition Authors: Yan Q
,
Gao X
,
Liu B,
Hou R,
He P,
Li Z,
Chen Q,
Wang J,
He J
,
Chen L
,
Zhao J
,
Xiong X
Sample: SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated)
Fitted models: 8zhn
Deposition Authors: Yan Q
,
Gao X
,
Liu B,
Hou R,
He P,
Li Z,
Chen Q,
Wang J,
He J
,
Chen L
,
Zhao J
,
Xiong X
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants.
Yan Q
,
Gao X
,
Liu B,
Hou R,
He P,
Ma Y,
Zhang Y,
Zhang Y,
Li Z,
Chen Q,
Wang J,
Huang X,
Liang H,
Zheng H,
Yao Y,
Chen X,
Niu X,
He J
,
Chen L
,
Zhao J
,
Xiong X
(2024) Nat Commun , 15 , 7585 - 7585
,
Gao X
,
Liu B,
Hou R,
He P,
Ma Y,
Zhang Y,
Zhang Y,
Li Z,
Chen Q,
Wang J,
Huang X,
Liang H,
Zheng H,
Yao Y,
Chen X,
Niu X,
He J
,
Chen L
,
Zhao J
,
Xiong X
(2024) Nat Commun , 15 , 7585 - 7585
Grant Support:
- Other government: 2021A1515011289 (China)
- Other government: SRPG22-002 (China)
- Other government: EKPG21-06 (China)
