EMD-60106

Single-particle
6.3 Å
EMD-60106 Deposition: 11/05/2024
Map released: 21/08/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-60106

SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C3 symmetry)

EMD-60106

Single-particle
6.3 Å
EMD-60106 Deposition: 11/05/2024
Map released: 21/08/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2, synthetic construct
Sample: SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C3 symmetry)
Fitted models: 8zhk

Deposition Authors: Yan Q , Gao X , Liu B, Hou R, He P, Li Z, Chen Q, Wang J, He J , Chen L , Zhao J , Xiong X
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants.
Yan Q , Gao X , Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J , Chen L , Zhao J , Xiong X
(2024) Nat Commun , 15 , 7585 - 7585
PUBMED: 39217172
DOI: doi:10.1038/s41467-024-51770-3
ISSN: 2041-1723