EMD-57387

Single-particle
3.0 Å
EMD-57387
3D View Gallery
Deposition: 08/04/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-57387

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-29ui summary report (pdf.gz) Map-29ui FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

FAM72A-UNG2 bound to the discoidin domain of substrate receptor MKLN1

EMD-57387

Single-particle
3.0 Å
EMD-57387
3D View Gallery
Deposition: 08/04/2026
Map released: 28/10/2026
Last modified: 28/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Structure of FAM72A-UNG2 bound to MKLN1 discoidin domain
Fitted models: 29ui

Deposition Authors: Sepic S, Du J, Maiwald SA , Schulman BA
Multimodal substrate recruitment enables CTLH MKLN1 E3 ligase to target acetylated N-, C-, and internal degrons.
Sepic S, Gottemukkala KV, Du J, Maiwald SA , Chrustowicz J , Papadopoulou EC , Stier LJ, von Gronau S, Schulman BA
(2026) Nat Commun , 17
PUBMED: 42892655
DOI: doi:10.1038/s41467-026-78311-4
ISSN: 2041-1723
Grant Support: