EMD-56598
XBP1u-stalled RPL4 RNC in complex with NAC
EMD-56598
Single-particle2.7 Å
Deposition: 05/02/2026Map released: 10/06/2026
Last modified: 24/06/2026
Sample Organism:
Homo sapiens
Sample: XBP1u-stalled RPL4 RNC in complex with NAC
Fitted models: 28ln
Deposition Authors: Santos J, Guennigmann M, Gora RJ, Iljina M, Predin M, Kotan IE, De P, Choudhary D, Jang J, Tippmann F, Hins C, Ban N
,
Tans SJ,
Shan S,
Kramer G,
Bukau B
Sample: XBP1u-stalled RPL4 RNC in complex with NAC
Fitted models: 28ln
Deposition Authors: Santos J, Guennigmann M, Gora RJ, Iljina M, Predin M, Kotan IE, De P, Choudhary D, Jang J, Tippmann F, Hins C, Ban N
,
Tans SJ,
Shan S,
Kramer G,
Bukau B
NAC promotes co-translational protein folding at the ribosomal tunnel exit.
Santos J,
Gunnigmann M,
Gora RJ,
Iljina M,
Predin M,
Kotan IE,
De P,
Choudhary D,
Jang J,
Tippmann F,
Hins C,
Ban N ,
Tans SJ,
Shan SO,
Kramer G,
Bukau B
(2026) Mol Cell , 86 , 1311 - 1326.e11
,
Tans SJ,
Shan SO,
Kramer G,
Bukau B
(2026) Mol Cell , 86 , 1311 - 1326.e11
Grant Support:
- European Research Council (ERC): SyG-101072047 (European Union)
- German Research Foundation (DFG): KR3593/4-1 (Germany)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM136321 (United States)
- National Science Foundation (NSF, United States): 2219287 (United States)
- Swiss National Science Foundation: 310030_212308 (Switzerland)
- European Molecular Biology Organization (EMBO): (European Union)
- Boehringer Ingelheim Fonds (BIF): (Germany)