EMD-56480

Helical reconstruction
2.7 Å
EMD-56480
3D View Gallery
Deposition: 26/01/2026
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56480
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9u02 summary report (pdf.gz) Map and 9u02 FULL report (pdf.gz)
EMICSS annotations (xml)

Medin fibril generated from the heterotypic interaction of Abeta40 and Medin.

EMD-56480

Helical reconstruction
2.7 Å
EMD-56480
3D View Gallery
Deposition: 26/01/2026
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: In vitro assembled Medin, resulting from the co-aggregation of recombinantly purified Amyloid Beta 40 peptide with synthetically produced Medin.
Fitted models: 9u02

Deposition Authors: Pradhan B, Kumar ST, Wagner J, Gallardo R, Zorzini V, Orlando G, Vleeschouwer MD, Madine J, Louros N, Neher J, Schymkowitz J, Rousseau F

Medin drives Abeta40 to adopt Abeta42-like fibril polymorphs in vitro
Pradhan B, Kumar ST, Wagner J, Gallardo R, Zorzini V, Orlando G, Vleeschouwer MD, Madine J, Louros N, Neher J, Schymkowitz J, Rousseau F
To Be Published