EMD-56105
The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).
EMD-56105
Single-particle2.6 Å
Deposition: 17/12/2025Map released: 01/07/2026
Last modified: 01/07/2026
Sample Organism:
Thermochaetoides thermophila
Sample: Complex of Chaetomium thermophilum Endoplasmic reticulum degradation enhancing mannosidase (CtEDEM) and Endoplasmic reticulum degradation enhancing protein disulfide isomerase (CtPDI)
Fitted models: 9tpa
Deposition Authors: Roversi P
,
Hitchman CJ
,
Lia A
,
Bayo Y
,
Gooptu B
Sample: Complex of Chaetomium thermophilum Endoplasmic reticulum degradation enhancing mannosidase (CtEDEM) and Endoplasmic reticulum degradation enhancing protein disulfide isomerase (CtPDI)
Fitted models: 9tpa
Deposition Authors: Roversi P
,
Hitchman CJ
,
Lia A
,
Bayo Y
,
Gooptu B
Structure and function of the EDEM:PDI ERAD checkpoint complex
Hitchman CJ
,
Lia A
,
Chiritoiu GN,
Munteanu CVA,
Ortigosa JR,
Ghenea S,
Savva C,
Wada I,
De Benedictis M,
Tax G,
Bayo Y
,
Crescioli I,
Alonzi DL,
Quigley A,
Modenutti CP,
Petrescu SM,
Santino A,
Gooptu B
,
Hosokawa N,
Roversi P
(2025) bioRxiv
,
Lia A
,
Chiritoiu GN,
Munteanu CVA,
Ortigosa JR,
Ghenea S,
Savva C,
Wada I,
De Benedictis M,
Tax G,
Bayo Y
,
Crescioli I,
Alonzi DL,
Quigley A,
Modenutti CP,
Petrescu SM,
Santino A,
Gooptu B
,
Hosokawa N,
Roversi P
(2025) bioRxiv
Grant Support:
- Wellcome Trust: 204801/Z/16/Z (United Kingdom)
- Wellcome Trust: 214090/Z/18/Z (United Kingdom)
- Italian National Research Council (CNR): Plant_EDEM (Italy)
