EMD-55658

Single-particle
2.95 Å
EMD-55658
3D View Gallery
Deposition: 12/11/2025
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55658
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9t7v summary report (pdf.gz) Map and 9t7v FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of LRRC58-EloB/C-CDO1 in complex with NEDD8-CUL5-RBX2-ARIH2-Ub

EMD-55658

Single-particle
2.95 Å
EMD-55658
3D View Gallery
Deposition: 12/11/2025
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: LRRC58-EloB/C-CDO1 in complex with NEDD8-CUL5-RBX2-ARIH2-Ub
Fitted models: 9t7v

Deposition Authors: Stier L, Andree GA, Schulman BA
Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1.
Andree GA, Stier LJ, Schmiederer K, Thielen AS, Schmid L, Maiwald SA, Gottemukkala KV, Du J, von Gronau S, Strasser C, Muller J, Henneberg LT, Guyot C, Kleiger G, Mann M, Murray PJ, Schulman BA
(2026) Nat Commun , 17
PUBMED: 42098103
DOI: doi:10.1038/s41467-026-72524-3
ISSN: 2041-1723
Grant Support: