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EMD-54805

Single-particle
2.23 Å
EMD-54805
3D View Gallery
Deposition: 15/08/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54805
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9sea summary report (pdf.gz) Map and 9sea FULL report (pdf.gz)
EMICSS annotations (xml)

Mouse otoferlin (216-1931) in complex with a lipid nanodisc (comprising 25% PS and 5% PIP2)

EMD-54805

Single-particle
2.23 Å
EMD-54805
3D View Gallery
Deposition: 15/08/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse otoferlin (216-1931) complexed with an MSP2N2 lipid nanodisc, comprising 25% PS and 5% PIP2
Fitted models: 9sea

Deposition Authors: Cretu C, Moser T
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.
Chen H, Cretu C, Trebilcock A, Evdokimova N, Babai N, Feldmann L, Leidner F, Benseler F, Mutschall S, Esch K, Szabo CZK, Pena V, Pape C, Grubmuller H, Strenzke N, Brose N, Wichmann C, Preobraschenski J, Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
PUBMED: 41091875
DOI: doi:10.1126/sciadv.ady8532
ISSN: 2375-2548
Grant Support: