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EMD-54802

Single-particle
3.43 Å
EMD-54802
3D View Gallery
Deposition: 15/08/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-54802
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9se5 summary report (pdf.gz) Map and 9se5 FULL report (pdf.gz)
EMICSS annotations (xml)

Mouse otoferlin (216-1931) in the lipid-free, Ca2+-bound state, "open" conformation (class 2)

EMD-54802

Single-particle
3.43 Å
EMD-54802
3D View Gallery
Deposition: 15/08/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse otoferlin (residues 216-1931) in the lipid-free, Ca2+-bound state
Fitted models: 9se5

Deposition Authors: Cretu C, Moser T
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.
Chen H, Cretu C, Trebilcock A, Evdokimova N, Babai N, Feldmann L, Leidner F, Benseler F, Mutschall S, Esch K, Szabo CZK, Pena V, Pape C, Grubmuller H, Strenzke N, Brose N, Wichmann C, Preobraschenski J, Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
PUBMED: 41091875
DOI: doi:10.1126/sciadv.ady8532
ISSN: 2375-2548