EMD-53880

Helical reconstruction
2.79 Å
EMD-53880
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Deposition: 21/05/2025
Map released: 15/10/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53880
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9raw summary report (pdf.gz) Map and 9raw FULL report (pdf.gz)
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The L1 amyloid-beta(1-40)fibril in the presence of anle138b (post-treatment)

EMD-53880

Helical reconstruction
2.79 Å
EMD-53880
3D View Gallery
Deposition: 21/05/2025
Map released: 15/10/2025
Last modified: 15/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The L1 amyloid-beta(1-40)fibril in the presence of anle138b (post-treatment)
Fitted models: 9raw

Deposition Authors: Frieg B, Han M, Griesinger C, Schroeder GF
Anle138b binds predominantly to the central cavity in lipidic A beta 40 fibrils and modulates fibril formation.
Han M, Frieg B, Matthes D, Leonov A, Ryazanov S, Giller K, Nimerovsky E, Stampolaki M, Xue K, Overkamp K, Dienemann C, Riedel D, Giese A, Becker S, de Groot BL, Schroder GF, Andreas LB, Griesinger C
(2025) Nat Commun , 16 , 8850 - 8850
PUBMED: 41044155
DOI: doi:10.1038/s41467-025-64443-6
ISSN: 2041-1723
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